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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APC
All Species:
16.06
Human Site:
S1223
Identified Species:
29.44
UniProt:
P25054
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25054
NP_000029.2
2843
311646
S1223
E
N
T
S
T
P
S
S
N
A
K
R
Q
N
Q
Chimpanzee
Pan troglodytes
XP_001143509
2844
311637
S1223
E
N
T
S
T
P
S
S
N
A
K
R
Q
N
Q
Rhesus Macaque
Macaca mulatta
XP_001095216
2303
243755
E729
V
R
K
Q
R
A
L
E
A
E
L
D
A
R
H
Dog
Lupus familis
XP_536285
2273
247246
C699
C
V
E
D
T
P
I
C
F
S
R
C
S
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61315
2845
311071
S1222
E
N
T
A
V
P
P
S
N
A
K
R
Q
N
Q
Rat
Rattus norvegicus
P70478
2842
310514
S1220
S
E
A
A
S
A
P
S
S
N
A
K
R
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511806
2844
309621
A1228
G
N
V
S
T
S
S
A
G
A
K
R
Q
G
Q
Chicken
Gallus gallus
XP_001233411
2232
244958
E658
D
H
R
Q
I
L
R
E
N
S
C
L
Q
T
L
Frog
Xenopus laevis
P70039
2829
310863
S1229
T
P
T
P
S
P
N
S
N
R
Q
N
Q
L
H
Zebra Danio
Brachydanio rerio
NP_001137312
2754
301074
S1167
P
S
K
K
G
M
F
S
H
S
K
T
S
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477152
2417
261266
Q843
D
D
S
V
K
C
Y
Q
T
E
D
T
P
Y
V
Honey Bee
Apis mellifera
XP_624558
2760
306907
N1184
P
Y
I
L
N
I
N
N
S
S
E
C
L
D
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783363
3212
346162
S1352
R
A
A
S
G
F
V
S
P
S
E
L
P
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
35
74.2
N.A.
90.4
90.1
N.A.
86.7
67.1
75
68
N.A.
23.8
22.8
N.A.
29.1
Protein Similarity:
100
99.5
49.4
76.1
N.A.
94.2
94.3
N.A.
92.7
72.2
84
78.2
N.A.
41
42
N.A.
45.1
P-Site Identity:
100
100
0
13.3
N.A.
80
6.6
N.A.
60
13.3
33.3
13.3
N.A.
0
6.6
N.A.
13.3
P-Site Similarity:
100
100
0
33.3
N.A.
86.6
40
N.A.
66.6
33.3
53.3
40
N.A.
20
46.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
16
16
0
16
0
8
8
31
8
0
8
0
8
% A
% Cys:
8
0
0
0
0
8
0
8
0
0
8
16
0
0
0
% C
% Asp:
16
8
0
8
0
0
0
0
0
0
8
8
0
16
0
% D
% Glu:
24
8
8
0
0
0
0
16
0
16
16
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
8
0
8
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
16
0
0
0
8
0
0
0
0
8
0
% G
% His:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
16
% H
% Ile:
0
0
8
0
8
8
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
16
8
8
0
0
0
0
0
39
8
0
0
0
% K
% Leu:
0
0
0
8
0
8
8
0
0
0
8
16
8
8
16
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
31
0
0
8
0
16
8
39
8
0
8
0
24
0
% N
% Pro:
16
8
0
8
0
39
16
0
8
0
0
0
16
0
0
% P
% Gln:
0
0
0
16
0
0
0
8
0
0
8
0
47
8
39
% Q
% Arg:
8
8
8
0
8
0
8
0
0
8
8
31
8
8
0
% R
% Ser:
8
8
8
31
16
8
24
54
16
39
0
0
16
16
16
% S
% Thr:
8
0
31
0
31
0
0
0
8
0
0
16
0
8
0
% T
% Val:
8
8
8
8
8
0
8
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
8
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _